Naturally Quiet Cravings & Support Satiety w/Calocurb Clinical
- Carrie Ballas FNP
- Nov 4
- 6 min read
A Season of Gratitude - and Temptation
The holiday season is about connection, comfort, and celebration — but it’s also the time when many people gain 3–5 pounds between late November and early January. Bigger portions, buffet-style meals, and social eating make it easy to lose control of appetite cues. This year, let’s change that story.
5 Reasons We Overeat During the Holidays
1. Bigger portions and endless options make it easy to ignore fullness.
2. Stress and emotions often trigger comfort eating.
3. Mindless eating while chatting or multitasking hides when we’re full.
4. Social pressure can override our natural satiety signals.
5. Sugary, fatty festive foods keep us coming back for “just one more bite.”
Introducing Calocurb Clinical (Amarasate®)
Developed from New Zealand bitter hops, Calocurb Clinical is a natural, evidence-based
supplement that helps the body regulate appetite and reduce cravings. It contains Amarasate®, a patented hops extract that works within your own biology to enhance fullness and satisfaction.
How it works -- the Science
Calocurb’s delayed-release capsule delivers Amarasate directly into the small intestine, where it activates bitter taste receptors (TAS2Rs) on gut enteroendocrine cells. This stimulation triggers the release of your body’s natural fullness hormones:
GLP-1 (Glucagon-Like Peptide-1): slows stomach emptying, signals satiety to the brain, and
improves glucose balance. CCK (Cholecystokinin): promotes fullness and reduces appetite by slowing digestion and communicating “I’m satisfied” to the brain.
Together, these hormones reduce hunger, quiet “food noise,” and support smaller, more
satisfying portions — naturally.
Key Features:
- Works within ~1 hour; effects last 4–6 hours
- No stimulants, caffeine, sugars, or artificial ingredients
- 100% plant-based, non-GMO, glyphosate-free
- Safe, simple, and non-habit-forming
-No prescription
Clinical Research Highlights
- Randomized, double-blind, crossover trial (healthy men): GLP-1 and CCK increased ~6×
baseline; calorie intake at an ad libitum lunch + snack was reduced by ~18%.
- Fasting study (healthy men): 80% reduction in hunger increases during a 24-hour fast (≈ 20% net hunger reduction overall).
- Fasting study (healthy women): 100% reduction in hunger and 120% reduction in food
cravings; rebound eating decreased by ~14%.
- Side effects: mild, short-lived laxative effect may occur during the first 1–3 days; avoid use in active GI inflammatory disease or type 1 diabetes.
How It Compares to GLP-1 Medications
Prescription GLP-1 analogs such as Semaglutide produce about 15–17% weight loss over 12
months, and dual GIP/GLP-1 agents such as Tirzepatide reach 20–26% loss after 72–88 weeks (Mayo Clinic, JAMA Network, NEJM). Calocurb Clinical doesn’t replace these medications but offers a natural, gentler way to influence the same pathways. It’s ideal for individuals who prefer non-prescription options, are not candidates for GLP-1 drugs, or are transitioning off GLP-1s and want to maintain results naturally.
Personalized Use & Versatility
Calocurb can be tailored to meet individual needs and health goals. It may be used for:
• General weight management and appetite control
• Transitioning off GLP-1 medications while maintaining results
• Perimenopausal weight gain or premenstrual appetite control
• Concurrent use with GLP-1 receptor agonists for additional appetite support
• Time-restricted eating or 5:2 intermittent fasting protocols
Customized dosing and integration plans are available through Boulder Integrative Health to fit your unique metabolism, lifestyle, and health goals.
Dosing & Tolerance
When starting Calocurb, it’s best to gradually increase the dose over the first five days to allow your body to adapt. This is why it’s key to get the “Starter Kit”
Some people may experience a mild laxative effect during the first 24–72 hours — this typically resolves on its own as the gut cells respond to the Amarasate® stimulation.
This gentle onboarding period helps ensure better tolerance and effectiveness.
Professional-Grade Support at BIH
Carrie has been using this product with her clients in the past year with great success and
minimal side effects.
Boulder Integrative Health now carries both Calocurb options:
- Calocurb (125 mg) — the original daily formula for gentle appetite and craving support.
- Calocurb Clinical (250 mg) — the professional-grade version offering double the Amarasate® dose for stronger activation of fullness hormones (GLP-1 and CCK).
Both contain the same patented New Zealand bitter hops extract (Amarasate®) and work
naturally to help reduce hunger and improve portion control.
Enjoy 20% OFF both Calocurb and Calocurb Clinical products from
Novemember 1 st -December 1 st 2025.
“I was out to brunch with a friend and ordered my normal food items, but because of the
Calocurb I’d taken an hour before, I only ate a quarter of my meal. I was so satiated — it was amazing!”
~Idella S. -BIH patient
Stay Ahead of Holiday-Season Weight Gain
Enjoy the flavors of the season while staying mindful:
- Take Calocurb ~1 hour before large meals
- Start with smaller portions
- Pause before seconds
- Focus on connection, not just the food
Small bites + strong boundaries = big wins for your health.
Tips for Supporting Satiety
Calocurb works best when paired with mindful eating and simple nutrition habits that support fullness and blood-sugar balance. Try incorporating these strategies:
Prioritize protein first. Eating protein at the start of your meal boosts GLP-1, stabilizes
blood sugar, and keeps you full longer.
Include healthy fats and fiber. Avocado, olive oil, nuts, seeds, and vegetables help slow
digestion and maintain satiety.
Start your day hydrated. A morning glass of warm water with lemon or apple cider
vinegar can gently stimulate digestion and support healthy metabolism.
Eat slowly and pause midway. It takes about 20 minutes for fullness hormones to signal
your brain — slowing down helps you recognize satisfaction sooner.
Stay consistent with meals. Skipping meals can lead to rebound hunger and cravings
later in the day.
These small adjustments amplify the effects of Calocurb, helping your body stay balanced and satisfied naturally.
Gratitude & Balance
The holidays are a time for gratitude, joy, and community, not guilt. By supporting your body’s
natural fullness signals, Calocurb helps you enjoy the celebrations and feel great afterward.
I’m thrilled to bring this evidence-based, natural option to our BIH community - a tool to help
you stay balanced, nourished, and confident through the holiday season.
With gratitude,
Carrie Ballas FNP
Boulder Integrative Health
Ask about Calocurb at your next BIH visit or reach out to our front desk to
place your order today!
⚠️ Note on canola oil
While I typically recommend avoiding seed oils, the canola oil in Calocurb serves a specific scientific purpose. It acts as an inert, stable carrier that allows the Amarasate® extract to disperse effectively along the gut surface, which is key to triggering the desired fullness hormone response. Importantly, this canola oil is cold pressed, GMO-free, and glyphosate-free— chosen for purity and function rather than as a dietary fat source.
How It Compares to GLP-1 Medications
Prescription GLP-1 analogs such as Semaglutide produce about 15–17% weight loss over 12 months, and dual GIP/GLP-1 agents such as Tirzepatide reach 20–26% loss after 72–88 weeks (Mayo Clinic, JAMA Network, NEJM). Calocurb Clinical doesn’t replace these medications but offers a natural, gentler way to influence the same pathways. It’s ideal for individuals who prefer non-prescription options, are not candidates for GLP-1 drugs, or are transitioning off GLP-1s and want to maintain results naturally.
Clinical Research Highlights
- Randomized, double-blind, crossover trial (healthy men): GLP-1 and CCK increased ~6× baseline; calorie intake at an ad libitum lunch + snack was reduced by ~18%.
- Fasting study (healthy men): 80% reduction in hunger increases during a 24-hour fast (≈ 20% net hunger reduction overall).
- Fasting study (healthy women): 100% reduction in hunger and 120% reduction in food cravings; rebound eating decreased by ~14%.
- Side effects: mild, short-lived laxative effect may occur during the first 1–3 days; avoid use in active GI inflammatory disease or type 1 diabetes.
Resources & References
- Official Calocurb Website: https://www.calocurb.com
-Amarasate® Research (Plant & Food Research, NZ): https://plantandfood.co.nz/amarasate
-Walker E et al. (2024). Gastrointestinal bitter taste receptors exhibit inter-regional and inter-
individual variation. Preprints. doi:10.20944/preprints202410.1917.v1
- Walker E et al. (2019). New Zealand bitter hops extract reduces hunger during a 24-hour
water-only fast. Nutrients, 11(11):2754.
- Walker E et al. (2024). Gastrointestinal delivery of bitter hops extract reduces appetite and
food cravings in healthy adult women undergoing acute fasting. Obesity Pillars, 11:100117.
- Kim SH et al. (2021). Effect of the GLP-1 analogue liraglutide versus placebo on circulating
proglucagon-derived peptides. Diabetes Obes Metab, 23:489–498.
